This church is annexed to the homonimous Congregation, founded in the 17th century for prayers offered to the souls in Purgatory. It has a single aisle with side chapels.
In the area of the apse, which is richly decorated with polychrome marbles, an alto-rilievo showing the winged skull together with similar works of art on the exterior, is testimony to the theme of death which is so deeply felt in the popular tradition of Naples.
Paintings by Massimo Stanzione, Andrea Vaccaro and Luca Giordano respectively adorn the main altar, the third chapel on the right and on the left of the aisle. Below the church (hypogeum) there is the ancient burial place.